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Ozgur Sahin

Ozgur Sahin, Ph.D.

Professor
Biochemistry & Molecular Biology
Cancer Focus

Elucidating the mechanisms of cancer therapeutics, drug resistance, and metastasis in breast cancer

Research Program
Developmental Cancer Therapeutics
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Research Interest

I am a Professor and Endowed Chair in Lipidomics, Pathobiology and Therapy in the Department of Biochemistry & Molecular Biology and Hollings Cancer Center at Medical University of South Carolina. Furthermore, I am an American Cancer Society (ACS) Research Scholar; founder, and president of LoxiGen, Inc.; and co-founder, and manager of OncoCube Therapeutics, LLC. My laboratory focuses on elucidating the mechanisms of cancer therapeutics, drug resistance and metastasis, mainly in breast cancer. We combine our expertise in cancer cell biology, functional transcriptomics/bioinformatics, and drug discovery, with those of the experts from the medicinal chemistry, proteomics, and medical oncology fields to target the most aggressive cancers.

Positions and Scientific Appointments

2022-Present: Co-Leader, Breast Transdisciplinary Cancer Team (TcT), MUSC Hollings Cancer Center, Charleston, SC, USA 2022-Present: Member, Developmental Cancer Therapeutics (DCT) Program, MUSC Hollings Cancer Center, Charleston, SC, USA 2022-Present: Professor and SmartState Endowed Chair, Department of Biochemistry & Molecular Biology, Medical University of South Carolina, Charleston, SC, USA 2023-Present: Scientific Advisory Board Member, A2A Pharmaceuticals, NY, USA 2021-Present: Founder and president, LoxiGen Inc., DE, USA 2020-Current: Co-founder and manager, OncoCube Therapeutics LLC, DE, USA 2017-2022: Associate Professor, Department of Drug Discovery and Biomedical Sciences, College of Pharmacy, University of South Carolina, Columbia, SC, USA 2017: Associate Professorship (Docent), Council of Higher Education of Turkey 2018-2020: Assistant Professor (unpaid leave), Department of Molecular Biology and Genetics and UNAM, Bilkent University, Ankara, Turkey 2013-2018: Assistant Professor, Department of Molecular Biology and Genetics and UNAM, Bilkent University, Ankara, Turkey 2012-2013: Instructor, Department of Molecular and Cellular Oncology, UT MD Anderson Cancer Center (MDACC), Houston, TX, USA

Education

Postdoctoral
December 2011
Cancer Cell Biology
German Cancer Research Center (DKFZ), Heidelberg, GERMANY
PhD
May 2008
Cancer Cell/Systems Biology
University of Heidelberg/German Cancer Research Center (DKFZ), Heidelberg, GERMANY
M.Sc.
April 2005
Molecular and Cellular Biology
University of Heidelberg, Heidelberg, GERMANY
B.Sc.
June 2003
Molecular Biology and Genetics
Middle East Technical University (METU), Ankara, TURKEY
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