Aguirre De Cubas, Ph.D.

I am an Assistant Professor of Pharmacology and Immunology at the Medical University of South Carolina (MUSC). My research program is focused on 1) understanding how cancers interact with the immune system, 2) identifying molecular determinants of tumoral immunogenicity and antigenicity, and 3) understanding how commonly lost epigenetic modifiers (SETD2, PBRM1, and BAP1) modify the tumor microenvironment and contribute to progression of clear cell renal cell carcinoma (ccRCC). To accomplish these goals, my research program operates at both dry and wet lab levels and brings a balanced skillset in genomics and bioinformatics, as well as cancer biology and immunology. Successful completion of this research will contribute to our knowledge of the mechanisms behind response to ICB in ccRCC. These novel discoveries would provide critical biological insights that ultimately could lead to novel clinical treatment strategies for ccRCC.

2021-Present: Assistant Professor, Medical University of South Carolina, SC, USA 2020-2021: Research Assistant Professor, Vanderbilt University Medical Center, Nashville, TN, USA 2015-2020: Post-Doctoral Research Fellow, Vanderbilt University Medical Center, Nashville, TN, USA 2009-2015: Ph.D. Fellow, Spanish National Cancer Research Centre (CNIO), Madrid, Spain 2008-2009: Research Assistant, Universidad de Zaragoza, Zaragoza, Spain