Michael Ostrowski

Michael Ostrowski, Ph.D.


Professor
Biochemistry & Molecular Biology
Cancer Focus

Signaling networks in the tumor microenvironment and how they impact tumor progression

Research Interest

I am the WH Folk Endowed Professor in the Department of Biochemistry and Molecular Biology in the College of Medicine, and Senior Advisor to the Director for the NCI–designated Hollings Cancer Center, Medical University of South Carolina. Our research is focused on the tumor microenvironment, with a recent focus on the mechanisms of immune suppression in the tumor microenvironment in pancreatic cancer. We have expertise in both the generation and analysis of GEMMs and orthotopic models of pancreatic cancer, including characterizing immune populations by flow cytometry and multi-spectral imaging. Our lab has been continually funded by NIH since 1985. For ten years I was PI on an NCI P01 grant "Genetic Analysis of the Breast Tumor Microenvironment" and currently am a Project Leader on a new P01 focusing on the tumor macroenvironment in cancer progression and cancer cachexia.

Positions and Scientific Appointments

2017-Present: WH Folk Endowed Professor of Experimental Oncology in the Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston SC 2017-Present: Senior Advisor to the Director, Hollings Cancer Center, Medical University of South Carolina, Charleston SC 2014-2017: Professor and Vice-Chair, Cancer Biology & Genetics Department, Ohio State University Medical Center, Columbus, OH 2010-2016: Co-Director, Solid Tumor Biology Program, Ohio State University Medical Center 2008-2014: Chair, Dean’s Basic Science Research Committee, College of Medicine, Ohio State University Medical Center 2006-2014: Professor & Chair, Molecular & Cellular Biochemistry Department, Ohio State University Medical Center, Columbus, OH 1999-2017: Co-Director, Molecular Biology & Cancer Genetics Program, Ohio State University Comprehensive Cancer Center 1999-2006: Professor, Molecular Genetics Department, Ohio State University, Columbus, OH 1995-1999: Associate Professor, Molecular Genetics Department, Ohio State University, Columbus, OH 1985-1995: Assistant Professor, Department of Microbiology & Immunology, Duke University Medical Center, Durham, NC 1983-1985: Senior Staff Fellow, Lab of Tumor Virus Genetics, National Cancer Institute, Bethesda, MD

Education

Fellowship
May 1983
Molecular Biology
National Cancer Institute, Lab of Tumor Virus Genetics, Bethesda, MD
PhD
January 1980
Chemistry
University of South Carolina, Columbia, SC
BS
May 1975
Chemistry
Illinois Benedictine College, Lisle, IL