Kristin Wallace, Ph.D.
Racial differences in immune and microbial responses and risk and outcomes in colorectal cancer
Research Interest
My research focuses on understanding differences in the tumor, lifestyle, and environmental factors as drivers of the racial disparities in colorectal neoplastic risk and outcomes (polyp recurrence, cancer recurrence, death). I have extensive experience with large-scale cancer prevention, multicenter clinical, and registry-based analysis, including SEER, the South Carolina Central Cancer Registry, and the Hollings Cancer Center Cancer Registry. Additionally, I have extensive experience working with community-based programs, including colorectal cancer screening in the southeast. With colleagues Dr. Alekseyenko and Dr. Obeid, we built the South Carolina Regional Colon Cancer Network (SCRCCN) to measure outcomes over time; we include EHR, registry, pathologic specimens, and outcomes. My primary research theme is understanding the role of inflammation and clinical, lifestyle, and genomic factors in driving the racial difference in colorectal neoplasia outcomes.