Hollings Cancer Center Members
Lynne Abruzzo, M.D., Ph.D.
Professor
Pathology & Laboratory Medicine
Research Program
Cancer Biology & Immunology
Cancer Focus
Pathogenesis of hematologic malignancies
Dauren Adilbay, M.D., Ph.D.
Assistant Professor
Otolaryngology
Research Program
Cancer Biology & Immunology
Cancer Focus
The Lab will focus on ways of molecular targeted imaging of malignant lesions to early detect, treat, and prevent cancer.
Tim Barnoud, Ph.D.
Assistant Professor
Biochemistry & Molecular Biology
Research Program
Cancer Biology & Immunology
Cancer Focus
Tumor suppressor genes, targeted therapy, and tumor cell intrinsic functions
Stefano Berto, Ph.D.
Assistant Professor
Neurosciences
Research Program
Cancer Biology & Immunology
Cancer Focus
My primary cancer research interest is applying advanced genomic and computational approaches to uncover the molecular mechanisms that drive tumor development, progression, and therapeutic response.
Steven Carroll, M.D., Ph.D.
Professor
Pathology & Laboratory Medicine
Research Program
Cancer Biology & Immunology
Cancer Focus
Our research program is focused on defining the mechanisms underlying the pathogenesis of NF1-associated peripheral nerve sheath tumors and using that information to develop effective new therapies for these neoplasms
Aguirre De Cubas, Ph.D.
Assistant Professor
Pharmacology & Immunology
Research Program
Cancer Biology & Immunology
Cancer Focus
Understanding how cancers interact with the immune system to identify molecular determinants of immunogenicity and developing strategies to modulate immunogenicity to enhance response to immune checkpoint blockade therapies. My program's second focus is to understand how commonly mutated chromatin modifiers/remodelers, namely SETD2, BAP1 and PBRM1, contribute to the development and progression of kidney, lung and skin cancers and leveraging synthetic lethal dependencies created by loss-of-function of these genes to develop rational, targeted therapies
Joe Delaney, Ph.D.
Associate Professor
Biochemistry & Molecular Biology
Research Program
Cancer Biology & Immunology
Cancer Focus
Mechanistic outcomes of aneuploidy in solid tumors, particularly high-grade serous ovarian cancer; RNA regulation
Evan Delgado, Ph.D.
Assistant Professor
Regenerative Medicine and Cell Biology
Research Program
Cancer Biology & Immunology
Cancer Focus
Liver cancer immune-oncology and metabolic heterogeneity
Stephen Duncan, Ph.D.
Professor
Regenerative Medicine and Cell Biology
Research Program
Cancer Biology & Immunology
Cancer Focus
Regulation of gene expression during endoderm formation and differentiation
Scott Eblen, Ph.D.
Associate Professor
Pharmacology & Immunology
Research Program
Cancer Biology & Immunology
Cancer Focus
Dr. Eblen focuses on molecular mechanisms and therapeutics involving protein kinases and E3 ubiquitin ligases in the context of ovarian and breast cancers.
Amy Engevik, Ph.D.
Assistant Professor
Regenerative Medicine and Cell Biology
Research Program
Cancer Biology & Immunology
Cancer Focus
Investigating the role of Myosin Vb in regulating proliferation, migration, cell adhesion and glucose metabolism in healthy and cancer states.
Kristen Engevik, Ph.D.
Assistant Professor
Regenerative Medicine and Cell Biology
Research Program
Cancer Biology & Immunology
Cancer Focus
My lab is focused on elucidating the role of epithelial purinergic signaling (an important route of cell communication) within gastrointestinal cancers, specifically colon cancer.
Melinda Engevik, Ph.D.
Associate Professor
Regenerative Medicine and Cell Biology
Research Program
Cancer Biology & Immunology
Cancer Focus
The study of how microbes influence cancer development and progression
Carol Feghali Bostwick, Ph.D.
Professor
Medicine
Research Program
Cancer Biology & Immunology
Cancer Focus
Development of cancer therapies
Leonardo Ferreira, Ph.D.
Assistant Professor
Pharmacology & Immunology
Research Program
Cancer Biology & Immunology
Cancer Focus
Engineering immune cells as living drugs for solid tumors
Vamsi Gangaraju, Ph.D.
Associate Professor
Biochemistry & Molecular Biology
Research Program
Cancer Biology & Immunology
Cancer Focus
Delineate the molecular mechanisms by which the Piwi-piRNA pathway silences transposons and maintains genome integrity
Radhika Gudi, Ph.D.
Assistant Professor
Pharmacology & Immunology
Research Program
Cancer Biology & Immunology
Cancer Focus
Oral cancer and cell biology
Silvia Guglietta, Ph.D.
Associate Professor
Regenerative Medicine and Cell Biology
Research Program
Cancer Biology & Immunology
Cancer Focus
Investigating the mechanisms linking the dysregulation of components of the innate immune system to the induction of intestinal inflammation, alterations of the intestinal microbiota and the development of CRC in colorectal cancer.
Denis Guttridge, Ph.D.
Professor
Pediatrics
Research Program
Cancer Biology & Immunology
Cancer Focus
NF-kB signaling in the regulation of the development and progression of adult (pancreatic) and childhood (rhabdomyosarcoma) tumors and associated quality of life syndromes including cachexia
Lu Han, Ph.D.
Assistant Professor
Biochemistry & Molecular Biology
Research Program
Cancer Biology & Immunology
Cancer Focus
Origin, heterogeneity and function of pancreatic cancer associated fibroblasts in modulating the pancreatic cancer microenvironment.
Azizul Haque, Ph.D.
Associate Professor
Pharmacology & Immunology
Research Program
Cancer Biology & Immunology
Cancer Focus
Studies in Dr. Haque's laboratory are probing the factors responsible for immune evasion by G-cell lymphomas. While MHC class I-restricted CD8+ T cells are effector cells in anti-tumor immune responses, MHC class II-restricted CD4+ T cells can play critical roles in initiating, regulating, and maintaining anti-tumor immune responses. Since most B-cell tumors express MHC class II molecules, these tumors can be potential target for CD4+ T cells.
Jessica Hartman, Ph.D.
Assistant Professor
Biochemistry & Molecular Biology
Research Program
Cancer Biology & Immunology
Cancer Focus
Mitochondrial/metabolic adaptations in cancer driven by changes in cytochrome P450 2E1 (CYP2E1) expression and subcellular localization and by changes in ploidy (genome copy number)
Elizabeth Hill, Ph.D.
Professor
Public Health Sciences
Research Program
Cancer Biology & Immunology
Cancer Focus
Biostatistics and Data Science
Aaron Hobbs, Ph.D.
Assistant Professor
Biochemistry & Molecular Biology
Research Program
Cancer Biology & Immunology
Cancer Focus
Mutant selective signaling in pancreatic cancer, the roles on metabolism, tumor microenvironment, and therapeutic sensitivity
Philip Howe, Ph.D.
Professor
Biochemistry & Molecular Biology
Research Program
Cancer Biology & Immunology
Cancer Focus
TGFβ and RNA proteins and their regulation of tumor progression
Andrew Jakymiw, Ph.D.
Associate Professor
Biomedical & Community Health Sciences
Research Program
Cancer Biology & Immunology
Cancer Focus
The study of RNA silencing-based therapies for cancer, in particular, the development of peptide carrier-mediated targeted delivery strategies of therapeutic small RNA molecules for the treatment of oral cancer
Judit Jimenez Sainz, Ph.D.
Assistant Professor
Biochemistry & Molecular Biology
Research Program
Cancer Biology & Immunology
Cancer Focus
BRCA and DNA repair related cancers (Variants of uncertain Significance)
Antonis Kourtidis, Ph.D.
Associate Professor
Regenerative Medicine and Cell Biology
Research Program
Cancer Biology & Immunology
Cancer Focus
Interaction of epithelial cell-cel adhesion complexes and RNA-binding proteins in post-transcriptional suppression of oncogenes and of pro-tumorigenic transformation
Carsten Krieg, Ph.D.
Assistant Professor
Pathology & Laboratory Medicine
Research Program
Cancer Biology & Immunology
Cancer Focus
My research is centered around finding novel enhanced cytokine formulations to immunotherapy of cancer.
Casey Langdon, Ph.D.
Assistant Professor
Pediatrics
Research Program
Cancer Biology & Immunology
Cancer Focus
Understanding how dysregulated subcellular localization contributes to tumorigenesis in both pediatric and adult cancers.
Amanda LaRue, Ph.D.
Professor
Pathology & Laboratory Medicine
Research Program
Cancer Biology & Immunology
Cancer Focus
The development of improved methods for the identification, purification, culture and transplantation of hematopoietic stem cells (HSCs)
David Long, Ph.D.
Professor
Biochemistry & Molecular Biology
Research Program
Cancer Biology & Immunology
Cancer Focus
Genome integrity and cancer predisposition
Patrick Mulholland, Ph.D.
Professor
Neurosciences
Research Program
Cancer Biology & Immunology
Cancer Focus
I am interested in how alcohol exacerbates risk for developing cancer.
David Mysona, M.D.
Assistant Professor
Obstetrics & Gynecology
Research Program
Cancer Biology & Immunology
Cancer Focus
I am focused on understanding the immune microenvironment of gynecologic malignancies particularly endometrial cancer.
Richard O'Neil, Ph.D.
Assistant Professor
Pharmacology & Immunology
Research Program
Cancer Biology & Immunology
Cancer Focus
Engineer T cells for oncology applications and study adaptive immunity in the context of cancer
Michael Ostrowski, Ph.D.
Professor
Biochemistry & Molecular Biology
Research Program
Cancer Biology & Immunology
Cancer Focus
Signaling networks in the tumor microenvironment and how they impact tumor progression
Jian Ouyang, Ph.D.
Assistant Professor
Biochemistry & Molecular Biology
Research Program
Cancer Biology & Immunology
Cancer Focus
Understanding and targeting genomic instability in cancers
Sophie Paczesny, M.D., Ph.D.
Professor
Pharmacology & Immunology
Research Program
Cancer Biology & Immunology
Cancer Focus
Understanding the mechanisms that regulate anti-cancer functions of immune cells and immune tolerance
Janardan Pandey, Ph.D.
Professor
Pharmacology & Immunology
Research Program
Cancer Biology & Immunology
Cancer Focus
Examining the roles of Fc (GM) and Fcg receptor genes in the pathogenesis of cancer
Jezabel Rodriguez-Blanco, Ph.D.
Assistant Professor
Pediatrics
Research Program
Cancer Biology & Immunology
Cancer Focus
Study of the mechanisms allowing brain tumors to relapse
Ozgur Sahin, Ph.D.
Professor
Biochemistry & Molecular Biology
Research Program
Cancer Biology & Immunology
Cancer Focus
Elucidating the mechanisms of cancer therapeutics, drug resistance, and metastasis in breast cancer
Natalie Saini, Ph.D.
Assistant Professor
Biochemistry & Molecular Biology
Research Program
Cancer Biology & Immunology
Cancer Focus
Mutagenic mechanisms that contribute to carcinogenesis
Christin Schmidt, Ph.D.
Assistant Professor
Neurosciences
Research Program
Cancer Biology & Immunology
Cancer Focus
My primary research interest is to develop human models for pediatric brain cancers, utilizing these to clarify mechanisms of tumor initiation, the role of the tumor microenvironment and to identify therapeutic vulnerabilities.
Souvik Seal, Ph.D.
Assistant Professor
Public Health Sciences
Research Program
Cancer Biology & Immunology
Cancer Focus
Bioinformatics/biostatistical problems originating from cancer datasets
Sara Sidles, Ph.D.
Assistant Professor
Pathology & Laboratory Medicine
Research Program
Cancer Biology & Immunology
Cancer Focus
Immunological mechanisms that drive inflammation and promote cancer progression
Ben Strickland, M.D.
Assistant Professor
Neurosurgery
Research Program
Cancer Biology & Immunology
Cancer Focus
Meningioma Immunotherapy
Chenthamarakshan Vasu, Ph.D.
Professor
Pharmacology & Immunology
Research Program
Cancer Biology & Immunology
Cancer Focus
Immune cell functions in autoimmune diseases
Noel Warfel, Ph.D.
Associate Professor
Biochemistry & Molecular Biology
Research Program
Cancer Biology & Immunology
Cancer Focus
Defining the role of hypoxia in prostate cancer metastasis and therapeutic resistance.
Brent Wilkerson, Ph.D.
Assistant Professor
Otolaryngology
Research Program
Cancer Biology & Immunology
Cancer Focus
Pathological mechanisms of cisplatin ototoxicity and testing of otoprotective treatments targeting angiogenesis and vascular function in the inner ear
Hai Yao, Ph.D.
Professor
Oral Health Sciences
Research Program
Cancer Biology & Immunology
Cancer Focus
Determine extracellular physical and chemical environment and its impact on cell energy metabolism
Ozlem Yilmaz, Ph.D., D.D.S.
Professor
Biomedical & Community Health Sciences
Research Program
Cancer Biology & Immunology
Cancer Focus
Role of Opportunistic Bacteria in Cancer Development and Response to Therapy
Huimin Zhang, Ph.D.
Assistant Professor
Biochemistry & Molecular Biology
Research Program
Cancer Biology & Immunology
Cancer Focus
Understanding the molecular mechanisms underlying genomic instability and exploring ways to target these mechanisms for cancer treatment.